Three-dimensional structure of a Nanobody® (modeled on the VHH with pdb-code 1U0Q, Cambillau et al). The target molecule is recognized by the surface formed by three hypervariable regions located at the top of the molecule (in green, cyan and blue). Hallmarks, amino acid residues that further differentiate a camelid VHH from a human VH, can be located at different positions within the framework regions, and here are coloured red, pink and magenta.

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Partnering With Us

The power of the Nanobody® platform is such that Ablynx has the opportunity to generate development candidates across a range of therapeutic areas in just over two years. The breadth of the Nanobody® platform and the efficiency with which leads are generated, has created partnering opportunities ranging from early-stage leads to clinical-stage licensing opportunities.

Ablynx continues to advance its own Nanobody® research and development programmes with the goal to build a unique proprietary pipeline. Ablynx will selectively choose to partner with companies who have therapeutic expertise in relevant disease areas and a significant commitment to development and commercialisation of biologics. Ablynx has an interest to explore partnerships where alternative routes of administration could offer an advantage over existing therapies. These may include delivery devices for inhalation or subcutaneous depot.

More information

To learn more about partnering opportunities with Ablynx, please contact Eva-Lotta Allan, Chief Business Officer for further information.